王彩云 讲师
工学博士,任职于必赢线路检测中心。专业方向为生物化工、毒理学。
E-mail:wangcy5683@czmc.edu.cn
研究领域:
环境污染物对哺乳动物的毒理效应与机制研究、公共卫生等
代表性科研项目:
(1) 国家自然科学基金,全氟壬烯氧基苯磺酸钠对小鼠肠屏障功能和脂质代谢的毒性风险规避探究(42407391),2025.1-2027.12,主持(立项)。
(2) 山西省自然科学基金,全氟壬烯氧基苯磺酸钠对肠炎恢复期小鼠肠屏障功能的毒理效应研究(202203021222313),2023.1-2025.12,主持(在研)。
(3) 山西省教育厅高校科技创新项目,N6-甲基腺苷(m6A)对OBS调节PPARγ表达干扰小鼠脂质代谢的作用机制研究(2022L360),2022.8-2024.8,主持。
教学工作:
(1) 毒理学基础(预防医学本科生专业课),参与。
(2) 预防医学(医学本科生专业基础课),参与。
(3) 环境卫生学实验课(预防医学本科生专业课),参与。
代表性论著:
(1) Jin C, Wang C(共一) Zhang C, et al. Imazalil resulted in glucolipid metabolism disturbance and abnormal m6A RNA methylation in the liver of dam and offspring mice. Ecotoxicology and environmental safety. 2024, 271: 115963.
(2)平飞飞, 王彩云, 牛敏瑶. 2022年长治市工作场所职业病危害因素监测分析. 环境与健康杂志. 2024, 41(6). 535-538.
(3)王彩云, 李桂霞, 靳远祥. 全氟壬烯氧基苯磺酸钠暴露对人源结肠癌细胞通透性的影响. 环境与健康杂志. 2023, 40(3): 219-225.(中文核心)
(4)Wang Caiyun, Fang C, Wang C, et al. Maternal sodium p-perfluorous nonenoxybenzene sulfonate exposure disturbed lipid metabolism and induced an imbalance in tyrosine metabolism in the F1 generation of mice. Chem Res Toxicol. 2022, 35(4): 651-662.
(5)Wang Caiyun, Weng Y, Tu W, et al. Maternal exposure to sodium ρ-perfluorous nonenoxybenzene sulfonate during pregnancy and lactation disrupts intestinal barrier and may cause obstacles to the nutrient transport and metabolism in F0 and F1 generations of mice. Sci Total Environ. 2021, 794: 148775.
(6)Wang Caiyun, Jin C, Tu W, et al. Maternal exposure of mice to sodium p-perfluorous nonenoxybenzene sulfonate causes endocrine disruption in both dams and offspring. Endocr J. 2021, 68(10): 1165-1177.
(7)Wang Caiyun, Zhao Y, Jin Y. The emerging PFOS alternative OBS exposure induced gut microbiota dysbiosis and hepatic metabolism disorder in adult zebrafish. Comp Biochem Physiol C Toxicol Pharmacol. 2020, 230: 108703.
(8)Wang Caiyun, Zhang Y, Deng M, et al. Bioaccumulation in the gut and liver causes gut barrier dysfunction and hepatic metabolism disorder in mice after exposure to low doses of OBS. Environ Int. 2019, 129: 279-290.
(9)Luo T, Wang Caiyun, Pan Z, et al. Maternal polystyrene microplastic exposure during gestation and lactation altered metabolic homeostasis in the dams and their F1 and F2 offspring. Environ Sci Technol. 2019, 53 (18): 10978-10992.
(10)Wan Z, Wang Caiyun, Zhou J, et al. Effects of polystyrene microplastics on the composition of the microbiome and metabolism in larval zebrafish. Chemosphere. 2019, 217: 646–658.